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The G protein-coupled receptors that the released agonists activate include the thrombin receptor (F2R), thromboxane A2 receptor (TBXA2R), and adenosine diphosphate (ADP) receptors (P2RY1 and P2RY12)

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Nutraceuticals, such as coenzyme Q10, offer an alternative to the aforementioned first-line treatment drugs, mostly owing to appreciably less or even a lack of side effects [78]